For Our Patients


Clinical Trials and Research

Clinical trials are designed to test the safety and efficacy of new approaches to preventing, detecting, and treating disease. Research and clinical trials also continuously look for new ways to use existing treatments, new drugs, surgical procedures and devices.

Florida Retina Institute clinical trial participants may enroll to possibly receive the newest treatment for their vitreoretinal conditions, as well as to have additional care and attention from clinical trial staff and with the results and outcome of their trial, help researchers find better treatments for future patients.

Detailed information about all Upcoming Studies

For Central Florida Patients

Sponsor: 4D Molecular Therapeutics, Inc.

Protocol Number: 4D-150-C003
Protocol name: (4DMT)
Treatment: IVT Indication: for Macular Neovascularization Secondary to Age-Related Macular Degeneration.


Sponsor: Adverum BioTechnologies, Inc.

Protocol Number: ADVM-022-12
Protocol Name: (Artemis)
Treatment: IVT
Indication: Neovascular Age-Related Macular Degeneration


Sponsor: Alcon

Protocol Number: RTE888-E001
Protocol Name: NOVA-1
Treatment: Implant
Indication: Neovascular Age-Related Macular Degeneration


Sponsor: Genentech

Protocol Number: MR45638
Protocol Name: Constance
Treatment: IVT
Indication: Neovascular Age-Related Macular Degeneration


Sponsor: ONL Therapeuticals

Protocol Number: ONL1204-GA-002
No Protocol Name
Treatment: IVT
Indication: Geographic Atrophy associated with Age-Related Macular Degeneration


Enroll in this Study

For North Florida Patients

Upcoming Soon!

R3918-AMD-2326/2327 Regeneron Pharmaceutics,INC - Dry AMD (GA)

A Randomized, Placebo-Controlled Study of Subcutaneous Pozelimab +
Cemdisiran Combination Therapy or Cemdisiran Monotherapy for the
Treatment of Georgraphic Atrophy, 284291


Wet AMD

ADVM-022-12 A Multi-Center, Randomized, Double-Masked, Active-Comparator-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Ixoberogene soroparvovec (Ixo-vec) in Participants with Neovascular Age-Related macular Degeneration (ARTEMIS)

4D-150-C003A Phase 3, Randomized, Double-Masked, Active-Controlled Trial of a Single Intravitreal Injection of 4D-150 in Adults with macular Neovascularization Secondary to Age-Related Macular Degeneration (4FRONT-1)

Diabetic Macular Edema

THAMES/ GR43828 A Phase I/II Study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of R07446603 administered alone or in combination with Aflibercept or Faricimab in patients with Diabetic Macula Edema

Non-Proliferative Diabetic Retinopathy

Vantage / VX01-DR-201 A Phase 2, Double-Masked, Randomized, Placebo-Controlled, Parallel design study to evaluate the efficacy and safety of orally administered VX-01 in Diabetic Retinopathy of Non-Proliferative type (NPDR)

Enroll in this Study

If you want to see a list of clinical trials, please click here and go to Clinicaltrials.gov, a resource provided by the U.S. National Library of Medicine. ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world.