For Central Florida Patients

Our Team of Doctors


Bachelor of Science (B.S.), Interdisciplinary Studies in Basic Biomedical Sciences Cum Laude, University of Florida, Gainesville, FL
Doctor of Medicine (M.D.), Cum Laude with Honors in Research, University of Florida College of Medicine, Gainesville, FL
Internship, Internal Medicine, Baylor College of Medicine, Houston, TX
Residency, Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, Houston, TX
Fellowship, Vitreoretinal Surgery and Diseases, University of Iowa Hospitals and Clinics, Iowa City, IA


Diplomate, American Board of Ophthalmology
Diplomate, National Board of Medical Examiners

Assocations and Affiliations

Orlando Health, Orlando Regional Medical Center
American Academy of Ophthalmology
American Medical Association
Florida Medical Association
American Society of Retina Specialists
Seminole County Medical Society
Rinehart Surgery Center Lake Mary, Orlando Health

Honors and Awards

P. J. Leinfelder Award for the Best Fellow Research Project, May 2013, University of Iowa
Hospitals and Clinics Ophthalmology Fellow Teaching Award, June 2012, University of Iowa
Hospitals and Clinics Cullen Eye Institute Goar Award for Resident Research, 1st Place
2nd Place, Baylor College of Medicine Lions Eye Bank Foundation Milton Boniuk Resident Research Award
Deanne Barlow Romrell Professionalism in Medicine Memorial Award, University of Florida College of Medicine
Lawrence M. Goodman Trust Award, Research Day Presentation Junior Alpha Omega Alpha National Medical Honor Society, merit based

Research Experience

Dr. Cunningham has extensive experience with research during his career. In medical school, he spent time at the National Eye Institute’s Laboratory of Ocular Immunology. During residency, he performed multiple research projects in the Ocular Surface Center at Baylor College of Medicine.
Dr. Cunningham has a particular interest in clinical trials. He currently serves as the Research Director at Florida Retina Institute, and is the Principal Investigator for multiple clinical trials including: Diabetic Retinopathy Clinical Research Network (DRCR) Protocol W, Protocol AC, and Protocol AD; Clearside TOPAZ Study; Allergan Phase 3 Abicipar Pegol; Chengdu Study for Neovascular Age-Related Macular Degeneration.

About Matthew A. Cunningham, MD

Doctor Cunningham holds a Bachelors of Science degree from the University of Florida and earned his medical degree, Cum Laude with Honors in Research, from the University of Florida College of Medicine. He completed an internship and ophthalmology residency at Baylor College of Medicine. Following residency training, Dr. Cunningham completed a fellowship in vitreoretinal surgery and diseases at the University of Iowa Hospitals and Clinics. Dr. Cunningham serves as an examiner for the American Board of Ophthalmology.

Doctor Cunningham joined Florida Retina Institute in 2013.


Dr. Cunningham enjoys traveling, biking, cardiovascular and weight training. He also enjoys spending time with his wife, children and friends.